PRP vs Rejuran for Acne Scar Recovery

June 14, 2026

PRP vs Rejuran for Acne Scar Recovery

PRP (Platelet-Rich Plasma) and Rejuran are both regenerative treatments commonly used in Korea to support acne scar recovery and improve overall skin quality. Rather than resurfacing the skin directly, both treatments promote natural healing and collagen production, although they differ significantly in their source materials and mechanisms of action.

What Is PRP?

PRP is created from the patient's own blood through a centrifugation process that concentrates platelets and growth factors.

Key features:

  • Uses the patient's own blood
  • Rich in natural growth factors
  • Promotes tissue repair
  • Supports collagen production
  • Improves skin healing
  • Often combined with microneedling or laser treatments

It is commonly used to accelerate skin regeneration and recovery.

What Is Rejuran?

Rejuran is a polynucleotide (PN) injectable derived from salmon DNA that focuses on repairing damaged skin and improving dermal health.

Key features:

  • PN-based regenerative treatment
  • Supports tissue repair and healing
  • Improves skin elasticity
  • Enhances hydration and skin barrier function
  • Promotes gradual collagen remodeling
  • Widely used for skin rejuvenation and acne scars

It is often chosen for improving long-term skin quality.

How They Improve Acne Scar Recovery

PRP:

  • Delivers concentrated growth factors
  • Promotes natural tissue healing
  • Supports collagen regeneration
  • Enhances recovery after procedures
  • Improves overall skin texture

Rejuran:

  • Stimulates skin repair mechanisms
  • Improves dermal strength
  • Enhances elasticity and hydration
  • Supports collagen production
  • Gradually smooths superficial acne scars

Both treatments focus on regeneration rather than aggressive resurfacing.

Treatment Experience and Downtime

PRP:

  • Requires a blood draw before treatment
  • Often combined with microneedling or injections
  • Mild redness after treatment
  • Minimal downtime
  • Recovery depends on the accompanying procedure

Rejuran:

  • Injectable treatment
  • Temporary papules at injection sites
  • Mild swelling or redness for 1–3 days
  • Short recovery period
  • Minimal interruption to daily activities

Results Timeline

PRP:

  • 2–4 weeks: early skin recovery
  • 1–3 months: gradual collagen stimulation
  • Continued improvement with multiple sessions

Rejuran:

  • 2–4 weeks: improved hydration and elasticity
  • 1–2 months: smoother skin texture
  • 3–6 months: ongoing regenerative effects
  • Best results typically achieved through multiple sessions

Average Cost in Korea

Pricing varies depending on the clinic, treatment protocol, and whether combination therapies are included.

Typical price ranges:

  • PRP: 200,000–500,000 KRW per session
  • Rejuran: 300,000–700,000 KRW per session
  • Combination treatments may cost more depending on the procedure

Multiple sessions are often recommended for noticeable acne scar improvement.

Which Is Better for Acne Scar Recovery?

Neither treatment is universally better—the choice depends on individual goals and skin condition.

PRP may be better if:

  • A natural, autologous treatment is preferred
  • Recovery after laser or microneedling is the priority
  • Overall skin regeneration is the main goal
  • Growth factor stimulation is desired

Rejuran may be better if:

  • Long-term skin repair is the priority
  • Skin barrier strengthening is needed
  • Skin elasticity and hydration need improvement
  • Mild acne scars and skin quality are the primary concerns

Some clinics may recommend combining regenerative treatments with lasers or RF microneedling for more comprehensive scar management.

Final Thoughts

PRP and Rejuran both support acne scar recovery by stimulating the skin's natural healing processes, but they do so through different mechanisms. PRP utilizes the patient's own growth factors to encourage regeneration, while Rejuran uses polynucleotides to repair and strengthen damaged skin. The most appropriate treatment depends on individual skin concerns, recovery goals, and the overall treatment plan.

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